Amaç
To evaluate the analgesic efficacy and adverse effects of tramadol and pethidine in pregnant women in labour.
Yöntem
Fifty-nine women reaching term were included in this study and evaluated into two groups, retrospectively. Group 1 received 100 mg pethidine intramuscularly, group 2 100 mg tramadol intramuscularly. Analgesic efficacy, maternal side effects namely; nausea and vomiting, fatigue and drowsiness, changes in the blood pressure and heart rate were assessed at 10, 30, 60, 120, 180, 240 minutes after administration of the study drugs. Progress of labour and fetal well-being at l.,5. minutes with AP-GAR scores were evaluated.
Bulgular
Pain relief effect was superior at 30 and 60.minutes in the pethidine group than tramadol. The frequencies of nausea and fatigue were higher in the tramadol group. Systolic and diastolic blood pressure decreased and heart rate increased after injection in both groups, but only the change in diastolic blood pressure showed a significant difference in pethidine group. There was no evidence of a difference between treatment groups in terms of vomiting and drowsiness, changes in diastolic blood pressure and heart rate, duration of labour, APGAR scores of neonates. There was no respiratory depression in the neonates.
Sonuç
These findings indicate that pethidine can be preferred to tramadol for obstetrical analgesia because of its superiority in analgesic efficacy with its low incidence of maternal adverse effects.
Anahtar Kelimeler
-