Amaç
SGB vaginal colonization of pregnant and newborn infection (early-late syndr.) is frequent. These newborn have an increased risk of serious illness, high mortality rate in first hours-days of life,and seriously ill after 2nd week. Women remain colonized for life and SGB infection risk it for next fetuses. Aim: To intervene to the pregnant for mild newborn infection, mild early syndr, to have time to intervene to the newborn without late syndr, for healthy newborn in new pregnancies.
Yöntem
For 6 years, 203 women were studied (positive vaginal, anal cultures), 123 (60,59% group a) with regular obstetric observation took peros ampiciline in pregnancy and before delivery 2gr iv, 21 (10,34% group b) were found positive culture due to ill newborn. The rest 56 (27,58% group c) positive-38 primepare-took iv amoxiciline for 7days (Igrx3) and 7days peros. Same therapy to 3 subgroup c1 out of pregnancy with SGB due to preterm deliveries. Therapy started in age 20-22 weeks, in delivery amoxiciline once iv 2gr From c group 2nd pregnancy 35(59,3%), 3rd 26(44,07%) and 1c1 woman delivered for a 2nd time. We observed 85 women a&b group in their next pregnancies, they took iv-peros amoxiciline in the same manner.
Bulgular
a&b newborns all from birth hospitalized; 1group & 2 b deaths, 11 late grave syndr in total. From c 12 needed hospitalization, 0 late syndr. Next births of all groups no death, mild newborn infection a&b group, without c group infection.
Sonuç
Amoxiciline IV administration for 7 days to SGB pregnant helps to have mild newborn infections, without late syndr. And no deaths; in next pregnancies newborns have almost no infection, without need for hospitalization.
Anahtar Kelimeler
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