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Ara
Dergi Kimliği
Online ISSN
1305-3132
Yayın Dönemi
1993 - 2021
Editor-in-Chief
Cihat Şen, Nicola Volpe
Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api
Color doppler in the diagnosis of fetal anemıa in pregnancy complicated by rhesus aloimmunization
A. Cirovic , V. Mandic , Z. Mikovic , N. Cerovic , D. Filimonovic
Künye
Color doppler in the diagnosis of fetal anemıa in pregnancy complicated by rhesus aloimmunization. Perinatoloji Dergisi 2002;10(3):254-255
Yazar Bilgileri
- Clinic Narodni Front Ob-Gyn Belgrade YU
Yayın Geçmişi
Çıkar Çakışması
Çıkar çakışması bulunmadığı belirtilmiştir.
Amaç
The diagnosis of fetal anemia is achieved either by amniocentesis or by cordocentesis. These invasive procedures are associated with complications, and, therefore, noninvasive methods are studied. During anemia the blood viscosity decreases and the blood velocity increases, so measuring medial cerebral artery (MCA) velocities can be useful in the prediction of fetal anemia. Our aim was to determine changes in MCA blood velocity of the anemic fetuses; relationship of these changes and fetal hemoglobin and haematocrit values; and to establish the significance of this method in the diagnosis of fetal anemia.
Yöntem
Clinical study was conducted during 1992-2000, and included 44 Rh-aloimmunised pregnant women who underwent cordocentesis in order to maintain fetal hemoglobin and haematocrit. Before the intervention we obtained MCA flow velocity waveforms of every fetus and registered pulsatily index (Pi) and mean velocity (Vmean). Only third trimester pregnancies (28-32. gestation weeks) with cephalic presentation were included in the study. MCA mean velocities were considered normal if ranged £ 21 cm/s. Based on the haematocrit all fetuses were divided in four groups: group 1-nonanemic ( > 140 g/l); group 2-mild anemia (120-139.9 g/l); group 3-moderate anemia (100-119.9 g/D; group 4-severe anemia, with the need for transfusion, (£ 99-9 g/l). We compared mean velocities between the groups and correlated mean velocities with the values of hemoglobin and haematocrit. Every fetus were taken only once in the study, no matter what the number of cordocentesis was.
Bulgular
Sonuç
In Rh- aloimmunised pregnancies anemic fetuses have increased mean blood velocities in MCA, especially in the cases of severe anemia. There is a negative correlation between mean velocities and hemoglobin and haematocrit . We suggest measuring mean blood velocities of the fetal MCA in the diagnosis of fetal anemia and in the determination of the time for cordocentesis.
The diagnosis of fetal anemia is achieved either by amniocentesis or by cordocentesis. These invasive procedures are associated with complications, and, therefore, noninvasive methods are studied. During anemia the blood viscosity decreases and the blood velocity increases, so measuring medial cerebral artery (MCA) velocities can be useful in the prediction of fetal anemia. Our aim was to determine changes in MCA blood velocity of the anemic fetuses; relationship of these changes and fetal hemoglobin and haematocrit values; and to establish the significance of this method in the diagnosis of fetal anemia.
Yöntem
Clinical study was conducted during 1992-2000, and included 44 Rh-aloimmunised pregnant women who underwent cordocentesis in order to maintain fetal hemoglobin and haematocrit. Before the intervention we obtained MCA flow velocity waveforms of every fetus and registered pulsatily index (Pi) and mean velocity (Vmean). Only third trimester pregnancies (28-32. gestation weeks) with cephalic presentation were included in the study. MCA mean velocities were considered normal if ranged £ 21 cm/s. Based on the haematocrit all fetuses were divided in four groups: group 1-nonanemic ( > 140 g/l); group 2-mild anemia (120-139.9 g/l); group 3-moderate anemia (100-119.9 g/D; group 4-severe anemia, with the need for transfusion, (£ 99-9 g/l). We compared mean velocities between the groups and correlated mean velocities with the values of hemoglobin and haematocrit. Every fetus were taken only once in the study, no matter what the number of cordocentesis was.
Bulgular
Of 44 fetuses, 15 didn't show the presence of anemia, 14 had mild anemia, 9 had moderate anemia, while severe anemia with the need for transfusion was registered in 6 cases. Mean velocity was: 18.33±0.78cm/s in group 1; 21.38±0.87cm/s in group 2; 22.67±1.12cm/s in group 3; and 24.85±1.44cm/s in group 4. All anemic fetuses had average mean MCA velocities higher compared to the nonanemic. in severe anemia mean velocities are higher than in moderate forms, showing statistical difference (p<0.05). Mean velocities are higher in severe forms showing negative correlation with hemoglobin and hematocrit values (p<0.05).
Sonuç
In Rh- aloimmunised pregnancies anemic fetuses have increased mean blood velocities in MCA, especially in the cases of severe anemia. There is a negative correlation between mean velocities and hemoglobin and haematocrit . We suggest measuring mean blood velocities of the fetal MCA in the diagnosis of fetal anemia and in the determination of the time for cordocentesis.
Anahtar Kelimeler
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Makale Türü Bildiri Özeti |
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Sayfalar 254-255 |
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Künye |
| Perinatoloji Dergisi 2002; 10 (3) |
| PDF Olarak İndir |