Amaç
Our aim was to determine the factors that could predict high birth weight based on possible maternal characteristics.
Yöntem
This retrospective case control study was performed in Baskent University Medical Faculty, Department of Obstetrics and Gynecology. 180 patients who gave birth to babies heavier than 4000 g between January 2000- January 2002 were selected. 72 nonsmoking, nondiabetic women with uncomplicated gestations who had enough data were admitted to the study (Group I). Control group (Group II) included 76 patients with uncomplicated singleton pregnancies who had delivered babies <4000g betvveen 37 and 42 weeks of gestation. Gestational age was confirmed by measuring crown rump length (CRL). Maternal weight, height, body mass index (BMI), parity, gestational age, 50 g oral glucose test value and second trimester maternal serum levels of alpha-fetoprotein (AFP), uncongugated estriol (uE3) and human chorionic gonadotropin (hCG) levels were compared in two groups. Univariate analysis was performed to detect parameters related with birth weights. Multiple linear regression analysis was used to detect independent risk factors to predict high fetal weight.
Bulgular
A total of 1706 deliveries occurred during the study period. The rate of macrosomic deliveries was 11 % (n=180). The mean birth weight of the study and control groups was 4216+247 and 3254±327 g respectively (p<0.001). Serum AFP levels in the study group (0.95±0.30) was lower than control group (1.21±0.48) (p<0.001). Gestational age at delivery was higher in the study group (39.89±1.20) than the control group (38.94+1.34) (p<0.001). Maternal parity, weight and body mass index also were higher in the study group (p<0.001). Univariate and multiple linear regression analysis confirmed that gestational age and AFP levels were independent risk factors that could predict birth weight.
Sonuç
Gestational age and serum AFP levels are independent predictive risk factors for high birth weight.
Anahtar Kelimeler
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