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Dergi Kimliği

Online ISSN
1305-3132

Yayın Dönemi
1993 - 2021

Editor-in-Chief
​Cihat Şen, ​Nicola Volpe

Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api

The importance of maternal serum interleukin-6 concentrations in diagnosis of subclinical intrauterine infections in pregnant women with preterm labor

A. Özkan , D. Öztürk , N. Tandoğan , G. Güran , E. Adalı , N. Süer

Künye

The importance of maternal serum interleukin-6 concentrations in diagnosis of subclinical intrauterine infections in pregnant women with preterm labor. Perinatoloji Dergisi 2002;10(3):240-240

Yazar Bilgileri

A. Özkan ,
D. Öztürk ,
N. Tandoğan ,
G. Güran ,
E. Adalı ,
N. Süer

  1. SSK Göztepe Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniği İstanbul TR
Yayın Geçmişi
Çıkar Çakışması

Çıkar çakışması bulunmadığı belirtilmiştir.

Amaç

To investigate the clinical imporlance of maternal serum interleukin-6 (il-6) measurements for diagnosis of asymptomatic intrauterine infection in women with preterm delivery.

Yöntem

 maternal serum il-6 concentrations have been measured in 61 pregnant women between 22. -34. Weeks of gestation. 39 were in preterm labor; 22 were in the control group. The placentas of 18 women who delivered in one week where tocolyses was not successful were sent to pathological analysis to investigate histological chorioamnionitis signs.

Bulgular

Average maternal serum il-6 concentrations of the group 1 with positive histochorioamnionitis and failing tocolyses who delivered in one week had been found significantly higher than in group 2 with successful tocolyses and positive histochorioamnionitis and in group 3 with failing tocolyses, who delivered in one week but had no signs of histochorioamnionitis (15 pg/ml versus 2.88 pg/ml and 6.40pg/ml). In order to predict preterm labor and histological chorioamnionitis during delivery, optimum sensitivity and specificity values of maternal serum il-6 concentrations have been found 5.9 pg/ml and above.

Tartışma
 
It has been seen that maternal serum il-6 concentrations of pregnant women with preterm labor associated with intrauterine infections were very high. The measurement of this cytokine may be beneficial for diagnosis and treatment of pregnant women who are high at preterm labor risks.
Anahtar Kelimeler

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