Amaç
in this study we aimed to research thyroid functions in healthy gravidas up to 20th Gestational age in cases which resulted by spontaneous abortion and to compare the relation of thyroid hormone concentration whith spontaneous abortion.
Yöntem
This research was performed in Sisli Etfal Training and Research Hospital 3rd Obstetrics and Gyneocology Department between March 2000 and August 2001. Thyroid functions of 40 gravidas whose gestations were normal until 6.-20th gestational weeks and 60 cases whose gestation resulted in spontaneous abortion were compared. Detailed history of patient of all gravidas was taken; systemic physical examinations and thyroid gland examinations were completed. Hemoglobine, hematocrite, blood group types. Total T3 (Triiodothyronine), Total T4 (Thyroxine), Free T3, Free T4. TSH (Thyroid Stimulating Hormone) levels were determinated.
Bulgular
100 cases were included in the study. Thyroid function tests of spontaneous abortion group (60/100) and the control group whose gestations were normal (40/100), were compared. Total T3, Total T4, Free T3, Free T4 levels were lower in the spontaneous abortion group and this was statistically significant (p< 0.001). TSH levels were found to be high and it was statistically significant (p< 0.01).
Sonuç
Disorders in thyroid functions have on important place in spontaneous abortion reasons. Examinations carried out carefully and detailed laboratory tests (TSH, Free and total thyroid hormones) of gravidas who have symptoms and signs of thyroid function defects, should be performed cases whose thyroid function defects are proved should be treated and followed as euthyroid for better maternal and fetal results.
Anahtar Kelimeler
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