Amaç
The aim of this study was to determine the effect of different iron supplements on Hb, hematocrit, etytrocytes indices and the other parameters in pregnancy population living at 1869 m altitude.
Yöntem
153 women between 18th and 23rd week of pregnancy were randomly divided into four groups. Women in the first, second and third groups were administered orally once per day: the preperation multivitamin; (=60 mg ferrous, 0.8 mg folic acide, 125 mg calcium. 100 mg magnesium. 100 mg; vitamine-C); Fe+3 (Ferro III hydroxyde polymaltose 100 mg+0.35 mg folic acide); Fe+2 (ferroglycin sulphate 225 mg) respectively. Women in the fourth group, control group, did not receive any medication. The results were compared in the groups (variance analysis with repeated measure) and inter groups (Anova).
Bulgular
Means Hb levels of 153 pıegnant women before treatment was 12.47±1.2 (9.4-16.4) g/dl. Hb levels of 17 (%11.11) pregnant women were lower than 11 g/dl. in pospartal period, Hb concentration was significantly higher in ihe first and third group than basal levels [p<0.001 (1.group), p<0.001 (3.group)]. Hb concentration in pospartal period was lower in the second and fourth group than basal levels in period before treatment [p<0.001 (2.group), p<0.001 (4.group)]. After delivery, concentrations of Hb were higher in the supplemented groups than control group [p<0.001 (1-4.groups), p=0.04 (2-4.groups), p<0.001 (3-4groups). Serum iron level was lower in the between 36 and 40.week of pregnancy than basal levels, in every four groups p<0.001 (1.group). p<0.001 (2.group), p<0.001 (3.group), p<0.001 (4.group). But in postpartal period, serum iron levels in supplemented groups were higher than between 36-40.weeks [p=0.03 (1.group), p<0.001 (2.group), p=0.02 (3.group). After delivery, serum iron levels in supplemented groups were higher than in control group [p<0.001 (1-4.groups), p<0.001 (2-4.groups), p<0.001 (3-4.groups). Serum ferritin level was higher in the first and third group than in control group (p=0.002 (1-4.groups), p=0.003 (3-4.groups)], and it was not significant difference between 2 and 4.groups (p>0.05), in postpartal period.
Sonuç
After delivery, all hematological indices in supplemented groups were better than in control group. This, pregnant women need iron supplementation during pregnancy. On account of all hematological indices, there was no significant difference between the first group receiving multivitamine and other two groups receiving iron (2. and 3.groups). Ferrous sulphate and multivilamine+Fe are the better supplementation regimen in pregnancy.
Anahtar Kelimeler
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