Amaç
The aim of the study was to determine the high risk group through 50-g, 1-hour glucose challenge before the 28th week and early diagnosis of Gestational Diabetes Mellitus (GDM).
Yöntem
As the result of 50-g, 1-hour oral glucose challenge test applied to 206 pregnant women who had a gestational period of 27 weeks and less, 100-g, 3-hour oral glucose tolerance test (100-g OGTT) was applied to 71 of the above mentioned having high values (>l40 mg/dl) in the risk group. After 50-g, 1-hour oral glucose challenge to 139 pregnant women in the control group that had a gestational period of 28 or more weeks, 100-g OGTT was employed on 54 of them in the risk group. Results were evaluated using National Diabetes Data Group (NDGG) criteria and because of at least two high values in 100-g OGTT, GDM was diagnosed. Blood glucose levels were measured in venous plasma by hexokinase method. GDM ratios were compared in both groups. in the analysis of the findings of randomized prospective study, t test and chi 2 test were employed, p<0.05 was found statistically significant. Findings: There was no statistically significant difference between study and control groups in age, gravidity, parity and abortus. To the pregnant women in the study group, an average of 22.5 (8-27) per week, to those in the control group an average of 31.5 (28-40) per week 50-g, 1-hour glucose challenge test was used. Out of 206 in the study group, 12 (5.82 %) GDM, out of 139 in the control group 7 (5.03 %) GDM were diagnosed and no statistically significant difference was found between them (p>0.05).
Bulgular
There is no need to wait for the 28th week in order to practise 50-g, 1-hour glucose challenge test to determine the risk group in terms of GDM in pregnancy. This test may very well be used safety in an earlier pregnancy period.
Anahtar Kelimeler
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