Perinatal outcome in women with asymptomatic (isolated) proteinurıa in late pregnancy

The aim of the study was to evaluate the influence of the asymptomatic (isolated) proteinuria in late pregnancy for the perinatal outcome.

Yöntem

The study covered 45 women with asymptomatic proteinuria in late pregnancy (the study group) and 136 healthy women (the control group). Proteinuria was 2,02+/-l,95 vs 0,2+/-0,3 g/24hours. Moreover, the women in both groups were at the same mean age: 27,6+/-6,17 vs 28,l+/-6,54 years (NS). The women in both group were at the same gestational age: 37,6+7/-2,62 vs 37,1+/- 2,15 (NS). Body mass index (BMI) before pregnancy was 23,8+/-2,79 vs 22,5+/- 2,60 (p<0,05). BMI before labor was 29,9+/-3,8 vs 27,7+/-2,8 (p<0,01). On average, BMI increased 24,5+/-9,7% vs 24,l+/-7,0 (NS). Mean arterial blood pressure was 123,0+/-15,4/76,1+/-12.0 mmHg vs 115+/-6,0/68,0+/-7,0 mmHg (p<0,01 and p<0,01). Three women in the study group presented lower extremities edema (6,67%). All women inclucled in the study have had measured renal function biochemical parameters (uric acid, urea, osmolality, creatinine, electrolytes, acid base balance) and they have had done blood morphology parameters. Moreover, all women inclucled in the study had no urinal tract infection (no bacteriuria present, leucocyturia within normal limits). Laboratory tests revealed hypoproteinemia 58,0+/-5,0 vs 67,0+/-6,0 g/l (p<0,001) and hypoalbuminemia 443,4+/-58,0 vs 522,0+/-87,0 umol/l (p<0,001). We compare in both groups percentage of primigravidas, weight and lenght of the newborn, ponderal index, Apgar score measured in 1 minute, percentage of caesarean sections.

Bulgular

There was 61,1 % primigravidas in the study group vs 48,5% in control group (NS). The mean weight of the newborn was 3596,8+/-664,7 vs 3356,8+/- 597,8 g (NS). The mean length of the newborn was 54,1+/-3,09 vs 53,3+/-3,31 cm (NS). The ponderal index was 22,57 +/- 2,07 vs 22,21+/-2,78 (NS). The 1- minute Apgar score was 9,8+/-0,77 vs 9,7+/-1,1 (NS). 22,2% patients in the study group had caesarean sections compared with 23,5% of patients in the control group (NS).

Sonuç

We conducted thal asymptomatic (isolated) proteinuria in late pregnancy does not effect perinatal outcome.

Anahtar Kelimeler

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