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Dergi Kimliği

Online ISSN
1305-3132

Yayın Dönemi
1993 - 2021

Editor-in-Chief
​Cihat Şen, ​Nicola Volpe

Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api

Il- 1 Alpha, il -1 Beta, il-6 and il- 8 in vagınal fluid of pregnant women with mycoplasma hominis and ureaplasma urealyticum infection

M. Wasiela , A. Pieczara , A. Pietrzak , E. Brzezinska-Blaszczyk , J. Kalinka

Künye

Il- 1 Alpha, il -1 Beta, il-6 and il- 8 in vagınal fluid of pregnant women with mycoplasma hominis and ureaplasma urealyticum infection. Perinatoloji Dergisi 2002;10(3):224-224

Yazar Bilgileri

M. Wasiela 1,
A. Pieczara 1,
A. Pietrzak 2,
E. Brzezinska-Blaszczyk 2,
J. Kalinka3

  1. Medical University of Lodz Department of Medical Microbiology Lodz PL
  2. Medical University of Lodz Division of Experimental Immunology Lodz PL
  3. Medical University of Lodz Department of Perinatology , Institute of Gynecology and Obstetrics Lodz PL
Yayın Geçmişi
Çıkar Çakışması

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Amaç

The purpose of this study was to determine the concentrations of the following cytokines: interleukin-1alpha (IL-1alpha), interleukin 1-beta (IL-1beta), interlukin 6 (IL-6), and interleukin 8 (IL-8) in vaginal fluid of pregnant women in relation to infection of genital mycoplasmas.

Yöntem

Samples of vaginal fluid were collected from 40 pregnant women. The cytokines concentrations (pg/mL) were measured by Standard enzyme-linked immunosorbent assay technique (ELISA).

Bulgular
 
Among 15 women genital mycoplasmas infections was diagnosed. Vaginal levels of interleukin-1alpha, interlekin-1beta, and interleukin- 6 vvere found to be significant elevated in women with mycoplasmas infection (127,11 pg/mL; 56,14 pg/mL; 22,08 pg/mL) as compared with patients without infection (76,16 pg/mL; 32,87 pg/mL; 15,13 pg/mL).

Sonuç

These findings suggest that measurement of cervicovaginal concentrations of selected cytokines may constitute a clinically useful marker of genital mycoplasmas infection. Relation between cytokines levels and risk of perinatal complications should be evaluated in further studies.
Anahtar Kelimeler

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