Antepartum risk factors associated with perinatal outcome in abruptio placentae

To evaluate clinical and laboratory risk factors associated with perinatal outcome in placental abruption.

Yöntem

Records of 126 patients with abruptio placentae were analyzed retrospectively. Maternal ages, parity, gestational age at birth, maternal complications (vaginal bleeding, placenta previa, hypertension, hypofibrinogenemia, postpartum operative intervention, blood transfusion requirements), birth weights, stillbirths, Apgar scores, neonatal care unit admissions were reviewed. Multiple logistic regression analyses used to derive maximum likelihood estimates of the adjusted odds ratios (OR) and 95% confidence intervals were used as measures of the association between pregnancy and outcome and antepartum factors.
Multiparity (p=>3) and hypertension was associated with an increase in risk with low Apgar scores (l'<4) (OR=2.8 and OR=2.0 respectively). Hypofibrinogenemia was associated with an increase in risk with stillbirth (OR=5.8), maternal blood trasfusion requirements (OR=5.3) and increased frequency of hysterectomy and/or hypogastric artery ligation (OR=6.6).

Sonuç

Gestational age at birth is the most important factor for fetal outcomes, where as maternal morbidity is dominated by maternal hypofibrinogenemia.

Anahtar Kelimeler

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