Effect of topical application of human milk , ethyl alcohol 96% and silver sulfadiazin on umbilical cord separation time in newborn infants

Amaç

Several agents have been used for neonatal umbilical cord care but we did not find any study to evaluate the effect of human milk on umbilical cord separation time Objective: To compare the effect of topical application of human milk, ethyl alchol 96 %, and silver sulfadiazin on umbilical cord separation time in newborn infants.

Yöntem

Primary-level newborn nursery at a university teaching hospital and a private hospital. Participant: Of 479 singleton near-term to full-term newborn enrolled, 312 completed the study Intervention: Newborns from birth were randomized to either 1) mother's milk group, 2) alcohol group, 3) silver sulfa group and 4) a control (no treatment ) group. Mother's milk for group 1, ethyl alcohol for group 2 and silver sulfadiazin ointment fo group 3 were started to apply to the umbilical stump three hours after birth and cotinued every eight hours till two days after umbilical cord separation. The time of umbilical cord separation and any discomfort like infection, hemorrhage and granuloma formation were reported by mothers.Nothing is applied to the umbilical stump of the conroll group and they received just dry cord care.

Bulgular

Mean ±1 SD cord separation time was statisticaly significantly different between four groups of study (breast milk group 124.64 ± 43hr, ethyl alcohol group 154.58 ±47 hr, silver sulfadiazin group 251.16 ±87 hr and for control group 158.53 ±52 hr (P = 0.0 0 1 ). No significant complication were observed in each group.

Sonuç

 Breast milk could substitute the other topical agents for umbilical cord care, but a multicenter study is required to advise it for routine umbilical cord care.