The effect of glucocorticoid therapy on prevention of early neonatal complications in preterm labors

Amaç

Premature birth is the single largest cause of perinatal mortality and morbidity in non anomalous infants in all developed nations.The aim of this study is to survey the role of glucocorticoid therapy in decreasing the early neonatal complications in preterm labors.

Yöntem This case control study has been carried out on 300 preterm labors which half of them received one to four doses of dexametasone 6 mg every 6 hours depending on the interval between admission untill delivery. Neonatal complications were comparisoned in two groups.

Bulgular

The mosl effectiveness of corton therapy on prevention of rşspiratory distress and neonatal mortality was observed in 29-34 gestational weeks and 700-1600 gr weights.There was a meaningful relation between corton doses and starting time with mortality of preterm neonates. Complications such as severe respiratory distress, sepsis, pnumonia, hyperbilirobinemia, were significantly lower in case group than control.

Sonuç

İt is recommended that all women high risk for preterm labor before 35 gestational weeks should receive corton at least 48 hours before delivery to reduce remarkably neonatal mortality and morbidity.

Anahtar Kelimeler

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