Arşiv
Ara
Dergi Kimliği
Online ISSN
1305-3132
Yayın Dönemi
1993 - 2021
Editor-in-Chief
Cihat Şen, Nicola Volpe
Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api
Placental apoptosıs in postterm pregnancies and its impact on neonatal outcome. Prelımınary results
Künye
Placental apoptosıs in postterm pregnancies and its impact on neonatal outcome. Prelımınary results. Perinatoloji Dergisi 2002;10(3):201-201
Yazar Bilgileri
- İnönü University Faculty of Medicine Department of Obstetrics and Gynecology Malatya TR
- Marmara University Faculty of Medicine Department of Pathology İstanbul TR
Yayın Geçmişi
Çıkar Çakışması
Çıkar çakışması bulunmadığı belirtilmiştir.
Amaç
To determine whether postterm pregnancy is associated with an increase in placental apoptosis and its impact on neonatal morbidity and mortality.
Yöntem
Bulgular
Out of 3622 deliveries, 51 (1.4%) of them were postterm. Mean maternal age wa.s 22.5±3.1. Gestational age was 40 weeks 6 days in 20 patients, 41 weeks 6 days in 24, 42 weeks 6 days in 5 and 43 weeks 6 days in 2 patients. Out of 51 pregnancies, 37 (72.5%) had spontaneous and 14 (27.5%) had induced labor. Mode of delivery was vaginal in 40 (78.4%) patients. Eleven patients had cesarean section tor intrapartum fetal distress. Mean neonatal weight was 3219-6g. Thin meconium was deteeted in 12 pregnancies. Neonatal morbidity and mortality were not detected. Bax and Bcl-2 expressions were assessed as mild (+), moderate (++), and severe (+++) and were evaluated in 20 patients . Seven of these patients had 40 weeks 6 days of gestation, 7 had 41 weeks 6 days, 5 had 42 weeks 6 days and 1 patient had 43 weeks 6 days of gestation. Decreased Bcl-2 expression was detected as gestational age progress suggesting excessive placental aging.
Sonuç
Although Bcl-2 expression was continued to decrease as gestation progress, it might not have an adverse effect on neonatal outcome.
To determine whether postterm pregnancy is associated with an increase in placental apoptosis and its impact on neonatal morbidity and mortality.
Yöntem
A prospecüve study was conducted among postterm singleton pregnancies without any maternal systemic disease from January 2000 to May 2002. Maternal age, gestational age at birth, mode of delivery. presence of meconium. İst and 5th minute Apgar scores, neonatal birth weight, umbilical artery pH and neonatal outcome were evaluated.
Bulgular
Out of 3622 deliveries, 51 (1.4%) of them were postterm. Mean maternal age wa.s 22.5±3.1. Gestational age was 40 weeks 6 days in 20 patients, 41 weeks 6 days in 24, 42 weeks 6 days in 5 and 43 weeks 6 days in 2 patients. Out of 51 pregnancies, 37 (72.5%) had spontaneous and 14 (27.5%) had induced labor. Mode of delivery was vaginal in 40 (78.4%) patients. Eleven patients had cesarean section tor intrapartum fetal distress. Mean neonatal weight was 3219-6g. Thin meconium was deteeted in 12 pregnancies. Neonatal morbidity and mortality were not detected. Bax and Bcl-2 expressions were assessed as mild (+), moderate (++), and severe (+++) and were evaluated in 20 patients . Seven of these patients had 40 weeks 6 days of gestation, 7 had 41 weeks 6 days, 5 had 42 weeks 6 days and 1 patient had 43 weeks 6 days of gestation. Decreased Bcl-2 expression was detected as gestational age progress suggesting excessive placental aging.
Sonuç
Although Bcl-2 expression was continued to decrease as gestation progress, it might not have an adverse effect on neonatal outcome.
Anahtar Kelimeler
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Makale Türü Bildiri Özeti |
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Sayfalar 201-201 |
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Künye |
| Perinatoloji Dergisi 2002; 10 (3) |
| PDF Olarak İndir |