Hellp syondrome versus severe preeclampsia remote from term

We aimed to determine whether HELLP syndrome at < 28 weeks of gestation is associated with an increased risk of maternal and fetal morbidity in comparison with the risk associated with severe preeclampsia without HELLP syndrome at a similar gestational age.

Yöntem

The medical records of 66 women being admitted to, High Risk Pregnancy Unit between 1996 - June 2001 with the diagnosis of either HELLP syndrome (n=32) or severe preeclampsia without HELLP syndrome (n=34) before < 28 weeks of gestation have been evaluated retrospectively.

Bulgular

The ultrasonographic gestational age at diagnosis, systolic blood pressure and hospitalization period were significantly different in two groups ( p<0,05). Nulliparity was more prevalent in HELLP syndrome group. The laboratory results were statistically different in two groups except for hemoglobin and fibrinogen results. There were no statistical difference in eclampsia complication, but the ratio of abrubtio placenta and transfusion of blood products were significantly higher in HELLP syndrome group. The delivery weights and perinatal exitus were not statistically different in both groups.

Sonuç

 it is recently shown in several reports that in the second trimester expectant management with aggressive monitoring of the status of both mother and fetus improves perinatal outcomes. On the hasis of the data reported in the literatüre: given that the expectant management in women with severe preeclampsia without HELLP syndrome at <32 weeks~ gestation improves neonatal outcome, the results of this study raise the issue regarding expectant management in women with the HELLP syndrome developing before 28,0 weeks gestation because perinatal and neonatal mortality and morbidity rates were statistically similar between the women with HELLP syndrome and those with severe preeclampsia.

Anahtar Kelimeler

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