Giriş
The aim of the study was to evaluate the relation between abnormal fetal heart rate (FHR) pattern and erythropoietin (EPO) levels in amniolic fluid, umbilical cord, maternal plasma and 1 and 5 minutes Apgar scores
Yöntem
Twenty one patients with abnormal FHR pattern on the nonstress test were included to this study. All of the patients undenvent cesarean section. Amniotic fluid, maternal and umbilical cord samples were obtained for measuring erythropoietin levels. We measured amniotic fluid EPO (A-EPO), maternal serum EPO (M-EPO) and umblical cord blood erythropoietin (U-EPO) levels using by radioimmunoassay. Apgar scores of 1 and 5 minutes were recorded.
Bulgular
U-EPO levels were found significantly higher than A-EPO levels (p<.05). There were no significant difference between the M-EPO, A-EPO. and between the U-EPO, M-EPO levels. Five of 21 patients had elevated U-EPO levels, but other 16 patients had normal levels of M-EPO, U-EPO and A-EPO. Four of 21 infants were low Apgar scores at 1 and 5 minutes. One of them had elevated U-EPO and normal M-EPO and A-EPO, whereas other three patients had normal A-EPO, M-EPO and U-EPO levels. On the other hand 17 infants showed normal Apgar score despite abnormal FHR pattern.
Sonuç
We conclude thal abnormal FHR pattern may signal imminent fetal risk but dont confirm fetal hypoxia. We did not find any correlation between abnormal FHR patterns and A-EPO, M-EPO. U-EPO levels, and Apgar scores of 1 and 5 minutes.
Anahtar Kelimeler
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