Newly born children, at the age 23-28 weeks are under a high risk of mortality and disablement. The difficulties of a final diagnosis of such cases are connected to diversity of CNS dysfunctions, the generalizalion of cerebral reactions, the dynamism of the process, and the changes of symptoms within several hours with the additional stress of the childbirth period. 120 newborns (age 1- 30 day) were investigated, together with a clinical investigation we used neurosonography, EEG, and in several cases cerebral MRI and an investigation of spinal liquor. All the neurological syndromes were classified according to the severity of the damage and the age of the patients. All patients were receiving the medicament Plaferon (Locally Produced) together with the symptomatic treatment. The results were remarkable: all the patients that were treated with the plaferon during the first 4-6 days adapted easier to the first afterbirth stress. There was observed a decrease of brain swelling and hypoxia, and there was an accelerated process of the mielinization. Also observed was an "awakening" effect of this medicament. The plaferon recommended itself as an anti hypoxic, anti toxic, immune corrective treatment.
The plaferon - type of interferon produced with viral induction by amniotic cells of human placenta- helps to create a positive influence for the newborns with trauma to adapt easier to their new environment.
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