Doppler Flow Velocity Waveforms in Umbilical and Middele Cerebral Arteries Before and After Cordocentesis

Amaç

To assess the effect of cordocentesis on the umbilical and fetal cerebral circulation.

Yöntem

In this corss-sectional study, 32 women underwent diagnostic cordocentesis at 20 to 32 weeks gestation. The pulsatility index (PI) in the umbilical artery (UA) and fetal middle cerebral artery (MCA) was measured by pulsed doppler ultrasound before and immediately after cordocentesis. Changes in the umbilical artery and middle cerebral artery PI were compared to investigate the effect of cordocentesis.

Bulgular

Cordocentesis was associated with a significant decrease in both umbilical artery PI was most marked when cordocentesis was performed transplacentally. The cases with high umbilical artery PI before cordocentesis, had umbilical venous pulsatile waveforms and in two of these cases, the PI values decreased after the procedure and venous pulsatile waveforms were dissappeared. The results were analyzed using SPSS version 6.0 and the significance of differences was determined by the paired Student's t-test and Wilcoxon test.

Sonuç

Acute alterations in the waveforms from both the umbilical and fetal cerebral circulation can be induced by cordocentesis. The decrease in resistance in the fetoplacental circulation could be attributed to release of vasodilators, and the increase in resistance observed in some cases could be secondary to arterial vasospasm.

Anahtar Kelimeler

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