Amaç
This prospective study was conducted to assess the prevalence of maternal colonization by genital mycoplasmas at early pregnancy and its association with preterm delivery (PD).
Yöntem
The high vaginal swabs from 179 randomly chosen pregnant women from Lodz region, Central Poland were cultured for Mycoplasma hominis and Ureaplasma urealyticum. The swabs were taken between 8 and 16 week of pregnancy. The course and pregnancy outcome in this cohort group was analyzed. The odds ratios (OR) and their CI were calculated using EPI INFO software.
Bulgular
68 (38,0%) of analyzed women were positive for genital mycoplasmas: 30(16,7%) for M. hominis and 38 (21,3%) for U. urealyticum. 21 (11,7%) women delivered before 37th completed week of pregnancy. Women with preterm delivery were more likely to be culture-positive for genital mycoplasmas (p=0,05) than those who delivered at term. Colonization of the lower genital tract by M. hominis and U. urealyticum was associated with increased risk of PD (OR=2,22 and OR=2,14; respectively)
Sonuç
The results of this study have shown that cervicovaginal infection of M. hominis and U.urealyticum at early pregnancy is associated with increased risk of preterm delivery. There is a need for detailed microbiological monitoring of all pregnant women at early pregnancy due to prematurity reduction in Poland.
Anahtar Kelimeler
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