Arşiv
Ara
Dergi Kimliği
Online ISSN
1305-3132
Yayın Dönemi
1993 - 2021
Editor-in-Chief
Cihat Şen, Nicola Volpe
Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api
Examination of TNF-A, il 6 and il-8 levels in maternal serum in pih cases
H. Çelik , E. Sapmaz , H. Akbulut , N. Tuğ , A. Altıngül Çelik , L.C. Beytur
Künye
Examination of TNF-A, il 6 and il-8 levels in maternal serum in pih cases. Perinatoloji Dergisi 2002;10(3):225-225
Yazar Bilgileri
- Fırat University , School of Medicine Department of Obstetrics and Gynecology Elazığ TR
- Fırat University , School of Medicine Department of Immunology Elazığ TR
Yayın Geçmişi
Çıkar Çakışması
Çıkar çakışması bulunmadığı belirtilmiştir.
Amaç
To compare TNF-a, IL-6 and IL-8 levels in maternal serum in pregnancy induced hypertension (PIH) cases both among themselves and with those of healthy pregnant women in a similar week of pregnancy.
Yöntem
Fifty six expectant women who came to our clinic between October 1, 2000 and December 1, 2001 and who were diagnosed as PIH (G1= mild pre-eclampsia, n=7; G2= severe pre-eclampsia, n=l4; G3=eclampsia, n=7) and healthy pregnant women (G4= control of G1, n=7; G5= control of G2, n=l4; G6= control of G4, n=7) who were in similar weeks of pregnancy and who comprise the control group were included in a randomised block design, cross-sectional prospective study program. TNF-a, IL-6 and IL-8 levels in maternal serum were investigated. Each PIH group was compared with its own control group (G1-G4, G2-G5, G3-G6) and then, among each other (G1-G2, G1-G3, G2-G3). Mann Whitney U test was used to compare continuous and ordinal data.
Bulgular
In all PIH groups, TNF-a, IL-6 and IL-8 levels were found to be higher than in their own control groups (p < 0.05, Mann Whitney U test). However, the comparison of PIH groups among themselves did not reveal any statistically significant difference (p > 0.03, Mann Whitney U test).
Sonuç
TNF-a, IL-6 and IL-8 levels in maternal serum in the pre-eclamptic and eclamptic cases increase in comparison to those in healthy pregnant cases. These levels do not show significant differences among themselves.
Anahtar Kelimeler
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Makale Türü Bildiri Özeti |
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Sayfalar 225-225 |
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Künye |
| Perinatoloji Dergisi 2002; 10 (3) |
| PDF Olarak İndir |